Glucose-6-Phosphate Dehydrogenase (G-6-PDH)
Trinity Biotech provides a range of tests and components for the quantitative and qualitative determination of Glucose-6-Phosphate Dehydrogenase (G-6-PDH)
- Quantitative Kinetic tests
- Qualitative screening test
- Qualitative Dye Reduction tests
Glucose-6-Phosphate Dehydrogenase (G-6-PDH) Deficiency is an X-linked disorder. Males who inherit an abnormal gene are invariably affected. Heterozygote females usually have approximately 50% G-6-PDH enzyme activity. It is most common in the Mediterranean, the Middle East, South East Asia and West Africa. It is rare among Caucasians.
Ultraviolet, Kinetic (quantitative)
Glucose-6-phosphate + NADP + G-6-PDH 6-PG + NADPH + H+
The rate of formation of NADPH is proportional to the G-6-PDH activity is measured spectrophotometrically as an increase in absorbance at 340nm.
Presentation is usually with an acute episode of intravascular haemolysis on exposure to certain drugs, infection or acute illness. Mediterranean forms may present with neonatal jaundice. The condition is also known as favism as sudden haemolysis may be precipitated by the ingestion of fava beans – Vicia faba. The deficiency is generally less severe in Africans and favism is rare in this population.
|G-6-PDH Trizma Buffer Solution||Trinity Biotech||400-4-50||50ml|
|G-6-PDH Deficiency Screen Kit||Trinity Biotech||400K-100-5X20||5 assays/vail 100 assays|
|G-6-PDH Deficiency Screen Kit||Trinity Biotech||400K-100X||10 assays/vail 100 assays|
|G-6-PDH Mineral Oil||Trinity Biotech||
|G-6-PDH Deficiency Screen Substrate||Trinity Biotech||400-10×10||10 assay vails-100 Assays|
|G-6-PDH Deficiency Screen Substrate||Trinity Biotech||400-5×10||5 assay vails-50 Assays|
|G-6-PDH Quantitative kit||Trinity Biotech||345-B||50 Assays|
|G-6-PDH Deficiency Screen by Spot Test kit||Trinity Biotech||203-a||50 Assays|
|G-6-PDH Control – Deficient||Trinity Biotech||G5888||6×0.5ml|
|G-6-PDH Control – Intermediate||Trinity Biotech||G5029||6×0.5ml|
|G-6-PDH Control – Normal||Trinity Biotech||G6888||6×0.5ml|
|G-6-PDH Red Cell Lysing Reagent||Trinity Biotech||R1129||4x25ml|